ISSN 1662-4009 (online)

ey0016.7-10 | Environmental Factors and Puberty | ESPEYB16

7.10. Is there a causal relationship between obesity and puberty?

T Reinehr , CL Roth

To read the full abstract: Lancet Child Adolesc Health. 2019 Jan;3(1):44–54.This article reviews cross-sectional, longitudinal and intervention studies regarding the bidirectional relationship between obesity and puberty.An increasing prevalence of obesity amongst children and adolescents is reported globally. Epidemiological cross-sectional and...

ey0018.11-6 | New insight: neurobiology and weight regulation | ESPEYB18

11.6. Child neurobiology impacts success in family-based behavioral treatment for children with obesity

EA Schur , SJ Melhorn , K Scholz , MRB De Leon , CT Elfers , MG Rowland , BE Saelens , CL Roth

Int J Obes (Lond). 2020 Oct;44(10):2011–2022. 10.1038/s41366-020-0644-1. https://pubmed.ncbi.nlm.nih.gov/32713944/Schur et al. addressed the question, whether responsiveness to visual food cues in functional magnetic resonance imaging (fMRI) is related to the treatment success of a 6-month Family-based Behavioral Treatment (...

ey0019.11-15 | Weight regulation and endocrine circuits (including interventions) | ESPEYB19

11.15. Impaired brain satiety responses after weight loss in children with obesity

CL Roth , SJ Melhorn , MRB De Leon , MG Rowland , CT Elfers , A Huang , BE Saelens , EA Schur

Christian.roth@deattlechildrens.org J Clin Endocrinol Metab. 2022; doi: 10.1210/clinem/dgac299. https://pubmed.ncbi.nlm.nih.gov/35544121/Brief Summary: In this intervention study, the effect of a 24-week family-based behavioral obesity intervention on brain activation, measured by v...

ey0020.9-12 | Obesity as a Brain Disease | ESPEYB20

9.12. Impaired brain satiety responses after weight loss in children with obesity

CL Roth , SJ Melhorn , MRB De Leon , MG Rowland , CT Elfers , A Huang , BE Saelens , EA Schur

Brief summary: Roth et al. studied the relationship between obesity outcomes and meal-induced changes in neural activation to high- versus low-calorie food cues before and after 24-week family-based behavioral treatment (FBT) in n=28 children (9–11 years) with obesity and in n=17 children of healthy weight without intervention (9–11 years). Among children with obesity who underwent FBT, unfavorable changes were observed in peripheral hormon...